Van de Ven Brace Halts Everton's Run at Brand New Home Ground
The Dutch defender became the initial backline player to net two goals in a Premier League game for Spurs since the Belgian defender in spring 2013.
At a glance
The Spurs defender heads home two times in opening period
The home side's Jake O'Brien has equalizer disallowed after VAR review
Pape Matar Sarr nets third in dying moments
The defeat is the Merseyside club's first at Hill Dickinson Stadium
The Tottenham defender scored on two occasions as Tottenham prolonged their winning streak in away games in the Premier League and delivered Everton their first defeat at their new home.
The Toffees were unbeaten in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after 133 years at the conclusion of last season.
But Tottenham's leader Van de Ven struck twice from corners in the first half to place their impressive record at jeopardy, and they were unable to mount a comeback before Pape Matar Sarr - set up by former Toffees attacker Richarlison - nodded in a final goal to seal the victory.
Jake O'Brien believed he had levelled the scores a short while after the defender's opener, directing a powerful header past the Spurs keeper from an Everton corner.
The Portuguese striker, in the meantime, missed a handful of opportunities, while Vicario made a series of excellent saves to ensure the London club went five matches on the road without defeat in the Premier League.
But the video assistant referee stepped in, advising Craig Pawson to check the goal on the screen and the referee ruled that Jack Grealish and Iliman Ndiaye were in an illegal position and had interfered with the Tottenham goalkeeper.
The win moves the manager's side up to third in the Premier League, five points off north London rivals and leaders Arsenal.
The Merseyside club remain in 14th position and are six points ahead of the drop zone.
Tottenham analysis: The defender excels in duties at both ends of pitch
Following a drab weekday display in the Champions League against Monaco, where they managed a mere two shots on target, Frank opted for the French striker up front instead of ex-Everton forward Richarlison.
The summer signing was failed to make much of an impact before being replaced for the substitute after 60 minutes on the field, but it emerged he proved unnecessary in the end.
Defender Van de Ven transformed into an offensive threat to be reckoned with.
Spurs' opening strike came from a well-worked set-piece play, with the midfielder heading the ball toward the six-yard box for an unmarked Van de Ven to score.
And Ven de Ven - stepping up as captain in the Argentine's absence - notched his second in added time as he rose above Jordan Pickford to nod in.
Van de Ven was just as impressive in defensive duties, combining effectively with Kevin Danso as the duo dealt excellently with the numerous deliveries thrown their way by the opposition.
Everton analysis: Toffees missing striker's instinct
Everton's new home had been a happy hunting ground, but it seems the freshness may have worn off somewhat and supporters flocked to the exits after Sarr's third for Spurs.
The end in the team's unbeaten home run will not be a major worry for the manager, but their striker situation are.
The forward and Thierno Barry - the Everton's two recognised centre-forwards - had netted only one league goal combined before Sunday's match.
And they were failed to add to that poor tally on a wet and gloomy evening on Merseyside.
Beto's performance was epitomized when he opted to bicycle-kick a golden opportunity from close range, despite having space and opportunity to readjust for a more conventional shot that would have tested Vicario.
Barry, too, failed to influence the game after replacing the starter in the 65th minute.
It wasn't for a lack of chance. Most of Everton's offensive moves came through the winger and Ndiaye, who tirelessly whipped dangerous crosses into the Tottenham box.
What next for both teams?
Everton: Moyes' men head to the Stadium of Light in the top flight on Monday, 3 November at 8 PM.
Tottenham: Spurs travel to Newcastle's ground on late October for their fourth-round League Cup match against Newcastle.